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Sequential Intravesical Mitomycin plus Bacillus Calmette-Guérin for Non-Muscle Invasive Urothelial Bladder Carcinoma: Translational and Phase I Clinical Trial

PURPOSE: To determine the safety and toxicities of sequential MMC + BCG in patients with non-muscle invasive bladder cancer (NMIBC) and explore evidence for potentiation of BCG activity by MMC. EXPERIMENTAL DESIGN: A 3+3 phase I dose-escalation trial of six weekly treatments was conducted in patient...

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Publicat a:Clin Cancer Res
Autors principals: Svatek, Robert S., Zhao, Xiang Ru, Morales, Edwin E., Jha, Mithilesh K., Tseng, Timothy Y., Hugen, Cory M., Hurez, Vincent, Hernandez, Javier, Curiel, Tyler J.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297588/
https://ncbi.nlm.nih.gov/pubmed/25424854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-1781
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