TGF-β2 secretion from RPE decreases with polarization and becomes apically oriented

Retinal pigmented epithelium (RPE) secretes transforming growth factor beta 1 and 2 (TGF-β1 and -β2) cytokines involved in fibrosis, immune privilege, and proliferative vitreoretinopathy (PVR). Since RPE cell polarity may be altered in various disease conditions including PVR and age-related macular...

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Bibliographic Details
Published in:Cytokine
Main Authors: Hirsch, Louis, Nazari, Hossein, Sreekumar, Parameswaran G., Kannan, Ram, Dustin, Laurie, Zhu, Danhong, Barron, Ernesto, Hinton, David R.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297550/
https://ncbi.nlm.nih.gov/pubmed/25496702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2014.11.014
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