Activin Upregulation by NF-κB is Required to Maintain Mesenchymal Features of Cancer Stem-like Cells in Non-Small Cell Lung Cancer

Soluble growth factors and cytokines within the tumor microenvironment aid in the induction of the epithelial-to-mesenchymal transition (EMT). Although EMT promotes the development of cancer-initiating cells (CICs), cellular mechanisms by which cancer cells maintain mesenchymal phenotypes remain poo...

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Bibliographic Details
Published in:Cancer Res
Main Authors: Wamsley, J. Jacob, Kumar, Manish, Allison, David F., Clift, Sheena H., Holzknecht, Caitlyn M., Szymura, Szymon J., Hoang, Stephen A., Xu, Xiaojiang, Moskaluk, Christopher A., Jones, David R., Bekiranov, Stefan, Mayo, Marty W.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297542/
https://ncbi.nlm.nih.gov/pubmed/25432175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-2702
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