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Induction of robust type-1 CD8(+) T-cell responses in WHO grade II low-grade glioma patients receiving peptide-based vaccines in combination with poly-ICLC

PURPOSE: WHO grade II low-grade gliomas (LGGs) with high risk factors for recurrence are mostly lethal despite current treatments. We conducted a phase I study to evaluate the safety and immunogenicity of subcutaneous vaccinations with synthetic peptides for glioma-associated antigen (GAA) epitopes...

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書誌詳細
出版年:Clin Cancer Res
主要な著者: Okada, Hideho, Butterfield, Lisa H., Hamilton, Ronald L., Hoji, Aki, Sakaki, Masashi, Ahn, Brian J., Kohanbash, Gary, Drappatz, Jan, Engh, Johnathan, Amankulor, Nduka, Lively, Mark O., Chan, Michael D., Salazar, Andres M., Shaw, Edward G., Potter, Douglas M., Lieberman, Frank S.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297523/
https://ncbi.nlm.nih.gov/pubmed/25424847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-1790
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