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Multi-cellular interactions sustain long-term contractility of human pluripotent stem cell-derived cardiomyocytes

Therapeutic delivery of cardiomyocytes derived from human pluripotent stem cells (hPSC-CMs) represents a novel clinical approach to regenerate the injured myocardium. However, poor survival and contractility of these cells are a significant bottleneck to their clinical use. To better understand the...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Burridge, Paul W, Metzler, Scott A, Nakayama, Karina H, Abilez, Oscar J, Simmons, Chelsey S, Bruce, Marc A, Matsuura, Yuka, Kim, Paul, Wu, Joseph C, Butte, Manish, Huang, Ngan F, Yang, Phillip C
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297340/
https://ncbi.nlm.nih.gov/pubmed/25628783
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