Amikacin in Newborn Infants: Comparative Pharmacology with Kanamycin and Clinical Efficacy in 45 Neonates with Bacterial Diseases

The pharmacokinetic properties of amikacin (BBK8) were similar to those of kanamycin in newborn infants. Peak serum concentrations of both drugs were in the range of 15 to 25 μg/ml with the exception of kanamycin in babies weighing greater than 2,000 g at birth where peak levels were 12.5 to 15 μg/m...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Howard, Jorge B., McCracken, George H., Trujillo, Hugo, Mohs, Edgar
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1976
Soggetti:	Pharmacology and Therapeutics
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429721/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/984762/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.10.2.205
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