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Laboratory Evaluation of 3-(5-Tetrazolyl)Penam, a New Semisynthetic Beta-Lactam Antibacterial Agent with Extended Broad-Spectrum Activity

In the new agent 3-(5-tetrazolyl)penam, hereafter referred to as CP-35,587, the carboxyl function at C3 in the penicillin nucleus has been replaced with the 5-tetrazolyl moiety. Marked changes in spectrum and resistance to gram-negative β-lactamases, particularly with regard to Klebsiella pneumoniae...

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Foilsithe in:Antimicrob Agents Chemother
Main Authors: English, Arthur R., Retsema, James A., Lynch, John E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 1976
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Rochtain Ar Líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429702/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/984745/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.10.1.132
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