STK-1, the human homolog of Flk-2/Flt-3, is selectively expressed in CD34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells.

We cloned the cDNA for stem cell tyrosine kinase 1 (STK-1), the human homolog of murine Flk-2/Flt-3, from a CD34+ hematopoietic stem cell-enriched library and investigated its expression in subsets of normal human bone marrow. The cDNA encodes a protein of 993 aa with 85% identity and 92% similarity...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Small, D, Levenstein, M, Kim, E, Carow, C, Amin, S, Rockwell, P, Witte, L, Burrow, C, Ratajczak, M Z, Gewirtz, A M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42968/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7507245/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.2.459
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