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Inactivation of Gentamicin by Penicillins in Patients with Renal Failure

Kinetics of gentamicin inactivation by carbenicillin and ticarcillin were studied in vitro and in 17 patients with renal failure. In vitro, the half-life of carbenicillin in human serum at 37 C is longer (19.2 ± 0.7 h) than ticarcillin (7.2 ± 0.6 h). Thus, incubation of gentamicin with equal concent...

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Bibliographic Details
Main Authors: Ervin, F. Richard, Bullock, Ward E., Nuttall, Charles E.
Format: Artigo
Language:Inglês
Published: 1976
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC429665/
https://ncbi.nlm.nih.gov/pubmed/938018
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