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High-Speed AFM Images of Thermal Motion Provide Stiffness Map of Interfacial Membrane Protein Moieties

[Image: see text] The flexibilities of extracellular loops determine ligand binding and activation of membrane receptors. Arising from fluctuations in inter- and intraproteinaceous interactions, flexibility manifests in thermal motion. Here we demonstrate that quantitative flexibility values can be...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nano Lett
Main Authors: Preiner, Johannes, Horner, Andreas, Karner, Andreas, Ollinger, Nicole, Siligan, Christine, Pohl, Peter, Hinterdorfer, Peter
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2014
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296598/
https://ncbi.nlm.nih.gov/pubmed/25516527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl504478f
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