Islet Transplantation in Type 1 Diabetic Patients Using Calcineurin Inhibitor-Free Immunosuppressive Protocols Based on T-Cell Adhesion or Costimulation Blockade

BACKGROUND: The applicability of islet transplantation as treatment for type 1 diabetes is limited by long-term graft dysfunction, immunosuppressive drug toxicity, need for multiple donors, and increased risk of allosensitization. We describe two immunosuppressive regimens based on the costimulation...

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Detalhes bibliográficos
Publicado no:Transplantation
Main Authors: Posselt, Andrew M., Szot, Gregory L., Frassetto, Lynda A., Masharani, Umesh, Tavakol, Mehdi, Amin, Raj, McElroy, Joan, Ramos, Marissa D., Kerlan, Robert K., Fong, Lawrence, Vincenti, Flavio, Bluestone, Jeffrey A., Stock, Peter G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296579/
https://ncbi.nlm.nih.gov/pubmed/20978464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e3181fe1377
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