COCAINE-INDUCED PROLIFERATION OF DENDRITIC SPINES IN NUCLEUS ACCUMBENS IS DEPENDENT ON THE ACTIVITY OF CYCLIN-DEPENDENT KINASE-5

Repeated exposure to cocaine produces an enduring increase in dendritic spine density in adult rat nucleus accumbens. It has been shown previously that chronic cocaine administration increases the expression of cyclin-dependent kinase-5 in this brain region and that this neuronal protein kinase regu...

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Pubblicato in:Neuroscience
Autori principali: Norrholm, S. D., Bibb, J. A., Nestler, E. J., Ouimet, C. C., Taylor, J. R., Greengard, P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2003
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296576/
https://ncbi.nlm.nih.gov/pubmed/12535933
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