Enzymatic Modification of Aminoglycoside Antibiotics: a New 6′-N-Acetylating Enzyme from a Pseudomonas aeruginosa Isolate

We describe an aminoglycoside 6′-N-acetyltransferase, isolated from Pseudomonas aeruginosa, that exhibits a novel substrate profile characterized by markedly reduced activity towards butirosin and amikacin.

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Bibliografiske detaljer
Main Authors: Haas, M., Biddlecome, S., Davies, J., Luce, C. E., Daniels, P. J. L.
Format: Artigo
Sprog:Inglês
Udgivet: 1976
Fag:
Chemistry; Mechanisms of Action and Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC429655/
https://ncbi.nlm.nih.gov/pubmed/820249
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