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Concentrations of Gentamicin and Amikacin in Human Kidneys

High kidney concentrations of gentamicin or amikacin, measured by an enzymological assay, were found in 9 of 10 patients who died during therapy with these aminoglycosides. Renal cortical concentrations of gentamicin ranged from 140 to 540 μg/g of tissue, with medullary levels of 128 to 230 μg/g. Co...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Edwards, Corwin Q., Smith, Craig R., Baughman, Kenneth L., Rogers, John F., Lietman, Paul S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1976
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429652/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/938022/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.9.6.925
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