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Mechanism of Action of Miconazole: Labilization of Rat Liver Lysosomes In Vitro by Miconazole

Miconazole, a potent antifungal agent, labilizes rat liver lysosomes. Its labilizing effect is followed by measuring the release of lysosomal hydrolases, namely, acid phosphatase, β-glucuronidase, and arylsulfatase A. The effect of miconazole is concentration dependent in the range of 10(−5) to 1.2...

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Bibliographic Details
Main Authors: Swamy, K. H. Sreedhara, Joshi, Aruna, Rao, G. Ramananda
Format: Artigo
Language:Inglês
Published: 1976
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC429648/
https://ncbi.nlm.nih.gov/pubmed/7188
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