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Essential roles of leucine-rich glioma inactivated 1 in the development of embryonic and postnatal cerebellum

Leucine-rich glioma inactivated 1 (LGI1) is a secreted protein that interacts with ADAM transmembrane proteins, and its mutations are linked to human epilepsy. The function of LGI1 in CNS development remains undefined. Here, we report novel functions of LGI1 in the generation of cerebellar granule p...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Xie, Ya-Jun, Zhou, Liang, Jiang, Nanwei, Zhang, Nan, Zou, Na, Zhou, Lin, Wang, Yin, Cowell, John K., Shen, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296302/
https://ncbi.nlm.nih.gov/pubmed/25591666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07827
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