Profilin-1 serves as a gatekeeper for actin assembly by Arp2/3-dependent and –independent pathways

Cells contain multiple F-actin assembly pathways including the Arp2/3 complex, formins, and Ena/VASP, which have largely been analyzed separately. They collectively generate the bulk of F-actin from a common pool of G-actin; however, the interplay/competition between these pathways remains poorly un...

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Publicado en:Dev Cell
Autores principales: Rotty, Jeremy D., Wu, Congying, Haynes, Elizabeth M., Suarez, Cristian, Winkelman, Jonathan D., Johnson, Heath E., Haugh, Jason M., Kovar, David R., Bear, James E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296256/
https://ncbi.nlm.nih.gov/pubmed/25543281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.10.026
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