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Targeting Therapy to The Neuromuscular Junction: Proof of Concept
INTRODUCTION: The site of pathology in myasthenia gravis (MG) is the neuromuscular junction (NMJ). Our goal was to determine the ability to direct complement inhibition to the NMJ. Methods: A single-chain antibody directed against the alpha subunit of the acetylcholine receptor was synthesized (scFv...
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| Vydáno v: | Muscle Nerve |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BlackWell Publishing Ltd
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4296224/ https://ncbi.nlm.nih.gov/pubmed/24037951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.24057 |
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