The Presence of the pAA Plasmid in the German O104:H4 Shiga Toxin Type 2a (Stx2a)–Producing Enteroaggregative Escherichia coli Strain Promotes the Translocation of Stx2a Across an Epithelial Cell Monolayer

BACKGROUND: A Shiga toxin type 2a (Stx2a)–producing enteroaggregative Escherichia coli (EAEC) strain of serotype O104:H4 caused a large outbreak in 2011 in northern Europe. Pathogenic mechanisms for this strain are unclear. We hypothesized that EAEC genes encoded on the pAA virulence plasmid promote...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Boisen, Nadia, Hansen, Anne-Marie, Melton-Celsa, Angela R., Zangari, Tonia, Mortensen, Ninell Pollas, Kaper, James B., O'Brien, Alison D., Nataro, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296181/
https://ncbi.nlm.nih.gov/pubmed/25038258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu399
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