The Yersinia pestis HmsCDE regulatory system is essential for blockage of the oriental rat flea (Xenopsylla cheopis), a classic plague vector

The second messenger molecule cyclic diguanylate (c-di-GMP) is essential for Y. pestis biofilm formation that is important for blockage-dependent plague transmission from fleas to mammals. Two diguanylate cyclases (DGCs) HmsT and Y3730 (HmsD) are responsible for biofilm formation in vitro and biofil...

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Udgivet i:Environ Microbiol
Main Authors: Bobrov, Alexander G., Kirillina, Olga, Vadyvaloo, Viveka, Koestler, Benjamin J., Hinz, Angela K., Mack, Dietrich, Waters, Christopher M., Perry, Robert D.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295937/
https://ncbi.nlm.nih.gov/pubmed/25586342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1462-2920.12419
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