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Mode of Action of the Polyene Antibiotic Candicidin: Binding Factors in the Wall of Candida albicans

The polyene antibiotic candicidin produces a rapid efflux of K(+) ions from a suspension of Candida albicans. Onset of K(+) leakage depends on the culture age, stationary-phase yeasts leaking K(+) more slowly than exponential-phase yeasts. The time taken for potassium leakage to begin represents the...

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Bibliographic Details
Main Authors: Hammond, S. M., Kliger, B. N.
Format: Artigo
Language:Inglês
Published: 1976
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC429577/
https://ncbi.nlm.nih.gov/pubmed/773298
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