PGC1α −1 Nucleosome Position and Splice Variant Expression and Cardiovascular Disease Risk in Overweight and Obese Individuals

PGC1α, a transcriptional coactivator, interacts with PPARs and others to regulate skeletal muscle metabolism. PGC1α undergoes splicing to produce several mRNA variants, with the NTPGC1α variant having a similar biological function to the full length PGC1α (FLPGC1α). CVD is associated with obesity an...

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Detalhes bibliográficos
Publicado no:PPAR Res
Main Authors: Henagan, Tara M., Stewart, Laura K., Forney, Laura A., Sparks, Lauren M., Johannsen, Neil, Church, Timothy S.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295622/
https://ncbi.nlm.nih.gov/pubmed/25614734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/895734
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