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Amino acid substitutions in the non-structural proteins 4A or 4B modulate the induction of autophagy in West Nile virus infected cells independently of the activation of the unfolded protein response

West Nile virus (WNV) is a neurotropic mosquito-borne flavivirus responsible for outbreaks of meningitis and encephalitis. Whereas the activation of autophagy in cells infected with other flaviviruses is well known, the interaction of WNV with the autophagic pathway still remains unclear and there a...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Blázquez, Ana-Belén, Martín-Acebes, Miguel A., Saiz, Juan-Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295549/
https://ncbi.nlm.nih.gov/pubmed/25642225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2014.00797
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