Connexin43 enhances the expression of osteoarthritis-associated genes in synovial fibroblasts in culture

BACKGROUND: Recent work has shown that the gap junction protein connexin43 (Cx43) is upregulated in cells of the joint during osteoarthritis (OA). Here we examined if the OA-associated increase in Cx43 expression impacts the function of synovial fibroblasts by contributing to the production of catab...

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Bibliografiske detaljer
Udgivet i:BMC Musculoskelet Disord
Main Authors: Gupta, Aditi, Niger, Corinne, Buo, Atum M, Eidelman, Eric R, Chen, Richard J, Stains, Joseph P
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295231/
https://ncbi.nlm.nih.gov/pubmed/25496568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-15-425
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