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Processing of Proopiornelanocortin by Insulin Secretory Granule Proinsulin Processing Endopeptidases()

A lysed preparation of isolated insulin secretory granules efficiently cleaved murine proopiomelanocortin (mPOMC) at physiologically important Lys-Arg processing sites. This processing was mostly attributed to an activity that co-eluted with the proinsulin processing type-II endopeptidase from anion...

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Publicat a:J Biol Chem
Autors principals: Rhodes, Christopher J., Thorne, Barbara A., Lincoln, Beth, Nielsen, Egon, Hutton, John C., Thomas, Gary
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295213/
https://ncbi.nlm.nih.gov/pubmed/8382698
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