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Methylnaltrexone: Its Pharmacological Effects Alone and Effects on Morphine in Healthy Volunteers

RATIONALE: Methylnaltrexone bromide (MTNX) is a peripherally acting mu-opioid receptor antagonist, prescribed for the treatment of opioid-induced constipation in patients with advanced illness who are receiving palliative care. Studies have used this drug to determine if other opioid-induced effects...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Psychopharmacology (Berl)
Hauptverfasser: Zacny, James P., Wroblewski, Kristen, Coalson, Dennis W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295206/
https://ncbi.nlm.nih.gov/pubmed/24871705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-014-3637-8
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