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Dual functions of NME1 in suppression of cell motility and enhancement of genomic stability in melanoma

The NME1 gene represents the prototypical metastasis suppressor, whose expression inhibits cell motility and metastasis without impact on primary tumor growth in a number of different human cancers. This report outlines our recent efforts to define the molecular mechanisms through which NME1 both su...

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Veröffentlicht in:Naunyn Schmiedebergs Arch Pharmacol
Hauptverfasser: Kaetzel, David M., Leonard, Mary K., Cook, Gemma S., Novak, Marian, Jarrett, Stuart G., Yang, Xiuwei, Belkin, Alexey M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294989/
https://ncbi.nlm.nih.gov/pubmed/25017017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-014-1010-4
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