Protective Effect of Cephalothin Against Gentamicin-Induced Nephrotoxicity in Rats

The possibility that the nephrotoxicity of gentamicin may be potentiated by the concomitant administration of cephalothin was examined in a rat model. Cephalothin given once daily in dosages up to 800 mg/kg per day for 10 days produced no renal damage. Gentamicin, at 6 to 50 mg/kg per day, caused pa...

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Détails bibliographiques

Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Dellinger, Patchen, Murphy, Terrence, Pinn, Vivian, Barza, Michael, Weinstein, Louis
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1976
Sujets:	Pharmacology and Therapeutics
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429495/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1259391/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.9.1.172
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