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Nuclear FAM21 participates in NF-κB-dependent gene regulation in pancreatic cancer cells

The pentameric WASH complex is best known for its role in regulating receptor trafficking from retromer-rich endosomal subdomains. FAM21 functions to stabilize the WASH complex through its N-terminal head domain and localizes it to endosomes by directly binding the retromer through its extended C-te...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Deng, Zhi-Hui, Gomez, Timothy S., Osborne, Douglas G., Phillips-Krawczak, Christine A., Zhang, Jin-San, Billadeau, Daniel D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294779/
https://ncbi.nlm.nih.gov/pubmed/25431135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.161513
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