Recombinant human Fab to glycoprotein D neutralizes infectivity and prevents cell-to-cell transmission of herpes simplex viruses 1 and 2 in vitro.

Herpes simplex viruses 1 and 2 (HSV-1 and -2) are associated with a number of conditions of varying severity, which are only partially responsive to current therapies. Human antibodies to the viruses offer a potential alternative. We describe here the generation of panels of human monoclonal Fab fra...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Burioni, R, Williamson, R A, Sanna, P P, Bloom, F E, Burton, D R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42946/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8278393/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.1.355
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