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Adenovirus E4ORF1-induced MYC activation promotes host cell anabolic glucose metabolism and virus replication

Virus infections trigger metabolic changes in host cells that support the bioenergetic and biosynthetic demands of viral replication. While recent studies have characterized virus-induced changes in host cell metabolism (Munger et al., 2008; Terry et al., 2012), the molecular mechanisms by which vir...

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Bibliographic Details
Published in:Cell Metab
Main Authors: Thai, Minh, Graham, Nicholas A, Braas, Daniel, Nehil, Michael, Komisopoulou, Evangelia, Kurdistani, Siavash K., McCormick, Frank, Graeber, Thomas G., Christofk, Heather R.
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294542/
https://ncbi.nlm.nih.gov/pubmed/24703700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.03.009
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