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ADI, autophagy and apoptosis: Metabolic stress as a therapeutic option for prostate cancer

Prostate cancer, the leading incidence of cancer in American males, is a disease in which treatment of nonlocalized tumors remains largely unsuccessful. These cancers lose expression of an arginine synthesis enzyme, argininosuccinate synthetase (ASS), and are susceptible to arginine deprivation by a...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Kim, Randie H., Bold, Richard J., Kung, Hsing-Jien
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294541/
https://ncbi.nlm.nih.gov/pubmed/19276647
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