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Autolytic Activation of Calpain 3 Proteinase Is Facilitated by Calmodulin Protein
Calpains are broadly distributed, calcium-dependent enzymes that induce limited proteolysis in a wide range of substrates. Mutations in the gene encoding the muscle-specific family member calpain 3 (CAPN3) underlie limb-girdle muscular dystrophy 2A. We have shown previously that CAPN3 knockout muscl...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4294526/ https://ncbi.nlm.nih.gov/pubmed/25389288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.588780 |
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