AMACR amplification and overexpression in primary imatinib-naïve gastrointestinal stromal tumors: a driver of cell proliferation indicating adverse prognosis

Non-random gains of chromosome 5p have been observed in clinically aggressive gastrointestinal stromal tumors, whereas the driving oncogenes on 5p remain to be characterized. We used an integrative genomic and functional approach to identify amplified oncogenes on 5p and to evaluate the relevance of...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Li, Chien-Feng, Chen, Li-Tzong, Lan, Jui, Chou, Fong-Fu, Lin, Ching-Yih, Chen, Yen-Yang, Chen, Tzu-Ju, Li, Shau-Hsuan, Yu, Shih-Chen, Fang, Fu-Ming, Tai, Hui-Chun, Huang, Hsuan-Ying
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2014
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294386/
https://ncbi.nlm.nih.gov/pubmed/25473890
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