Apoptin enhances the oncolytic properties of vaccinia virus and modifies mechanisms of tumor regression

A recombinant vaccinia virus VVdGF-ApoS24/2 expressing apoptin selectively kills human cancer cells in vitro [Kochneva et al., 2013]. We compared the oncolytic activity of this recombinant with that of the parental strain L-IVP using a model of human A431 carcinoma xenografts in nude mice. Single in...

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Udgivet i:Oncotarget
Main Authors: Kochneva, Galina, Zonov, Evgeniy, Grazhdantseva, Antonina, Yunusova, Anastasiya, Sibolobova, Galina, Popov, Evgeniy, Taranov, Oleg, Netesov, Sergei, Chumakov, Peter, Ryabchikova, Elena
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294355/
https://ncbi.nlm.nih.gov/pubmed/25358248
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