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Myeloid-Derived Suppressor Cells Impair Alveolar Macrophages through PD-1 Receptor Ligation during Pneumocystis Pneumonia

Myeloid-derived suppressor cells (MDSCs) were recently found to accumulate in the lungs during Pneumocystis pneumonia (PcP). Adoptive transfer of these cells caused lung damage in recipient mice, suggesting that MDSC accumulation is a mechanism of pathogenesis in PcP. In this study, the phagocytic a...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Lei, Guang-Sheng, Zhang, Chen, Lee, Chao-Hung
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294265/
https://ncbi.nlm.nih.gov/pubmed/25404033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02686-14
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