Impact of the glpQ2 Gene on Virulence in a Streptococcus pneumoniae Serotype 19A Sequence Type 320 Strain

Glycerophosphodiester phosphodiesterase (GlpQ) metabolizes glycerophosphorylcholine from the lung epithelium to produce free choline, which is transformed into phosphorylcholine and presented on the surfaces of many respiratory pathogens. Two orthologs of glpQ genes are found in Streptococcus pneumo...

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Vydáno v:Infect Immun
Hlavní autoři: Chuang, Yi-Ping, Peng, Zih-Rong, Tseng, Shun-Fu, Lin, Yu-Chun, Sytwu, Huey-Kang, Hsieh, Yu-Chia
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Molecular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294258/
https://ncbi.nlm.nih.gov/pubmed/25422269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02357-14
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