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Protection from Systemic Candida albicans Infection by Inactivation of the Sts Phosphatases

The human fungal pathogen Candida albicans causes invasive candidiasis, characterized by fatal organ failure due to disseminated fungal growth and inflammatory damage. The suppressor of TCR signaling 1 (Sts-1) and Sts-2 are two homologous phosphatases that negatively regulate signaling pathways in a...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Naseem, Shamoon, Frank, David, Konopka, James B., Carpino, Nick
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294239/
https://ncbi.nlm.nih.gov/pubmed/25422266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02789-14
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