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The 5-lipoxygenase pathway: oxidative and inflammatory contributions to the Alzheimer’s disease phenotype

Alzheimer’s disease (AD) is the most common, and, arguably, one of the most-well studied, neurodegenerative conditions. Several decades of investigation have revealed that amyloid-β and tau proteins are critical pathological players in this condition. Genetic analyses have revealed specific mutation...

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Publicat a:Front Cell Neurosci
Autors principals: Joshi, Yash B., Praticò, Domenico
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294160/
https://ncbi.nlm.nih.gov/pubmed/25642165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00436
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