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Hyperglycemia Induces Toll-Like Receptor-2 and -4 Expression and Activity in Human Microvascular Retinal Endothelial Cells: Implications for Diabetic Retinopathy

Diabetic retinopathy (DR) causes visual impairment in working age adults and hyperglycemia-mediated inflammation is central in DR. Toll-like receptors (TLRs) play a key role in innate immune responses and inflammation. However, scanty data is available on their role in DR. Hence, in this study, we e...

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Detalhes bibliográficos
Publicado no:J Diabetes Res
Main Authors: Rajamani, Uthra, Jialal, Ishwarlal
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293793/
https://ncbi.nlm.nih.gov/pubmed/25610879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/790902
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