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New N-Aryl-N’-(3-(substituted)phenyl)-N’-methylguanidines as Leads to Potential PET Radioligands for Imaging the Open NMDA Receptor

An expansive set of N-aryl-N’-(3-(substituted)phenyl)-N’-methylguanidines was prepared in a search for new leads to prospective PET ligands for imaging of the open channel of the N-methyl-D-aspartate (NMDA) receptor in vivo. The N-aryl rings and their substituents were varied, whereas the N-methyl g...

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Foilsithe in:Bioorg Med Chem Lett
Main Authors: Naumiec, Gregory R., Cai, Lisheng, Pike, Victor W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293695/
https://ncbi.nlm.nih.gov/pubmed/25499436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.11.066
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