Profiling of cis-Diol-containing Nucleosides and Ribosylated Metabolites by Boronate-affinity Organic-silica Hybrid Monolithic Capillary Liquid Chromatography/Mass Spectrometry

RNA contains a large number of modified nucleosides. In the metabolic re-exchange of RNA, modified nucleosides cannot be recycled and are thus excreted from cells into biological fluids. Determination of endogenous modified nucleosides in biological fluids may serve as non-invasive cancers diagnosti...

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Udgivet i:Sci Rep
Main Authors: Jiang, Han-Peng, Qi, Chu-Bo, Chu, Jie-Mei, Yuan, Bi-Feng, Feng, Yu-Qi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293604/
https://ncbi.nlm.nih.gov/pubmed/25585609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07785
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