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Concomitant analysis of Helios and Neuropilin-1 as a marker to detect thymic derived regulatory T cells in naïve mice

Regulatory T (Treg) cells are characterized by the expression of CD4, CD25 and the intracellular Foxp3. However, these markers do not indicate whether Treg cells are thymic derived Treg (tTreg) cells or peripherally induced Treg (pTreg) cells. Recently, Helios and Neuropilin-1 (Nrp1) has been report...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Singh, Kailash, Hjort, Marcus, Thorvaldson, Lina, Sandler, Stellan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293597/
https://ncbi.nlm.nih.gov/pubmed/25586548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07767
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