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Sequential conformational rearrangements in flavivirus membrane fusion

The West Nile Virus (WNV) envelope protein, E, promotes membrane fusion during viral cell entry by undergoing a low-pH triggered conformational reorganization. We have examined the mechanism of WNV fusion and sought evidence for potential intermediates during the conformational transition by followi...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Chao, Luke H, Klein, Daryl E, Schmidt, Aaron G, Peña, Jennifer M, Harrison, Stephen C
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293572/
https://ncbi.nlm.nih.gov/pubmed/25479384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04389
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