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Comparative Clinical Pharmacology of Gentamicin, Sisomicin, and Tobramycin

Using a randomized crossover design involving 12 normal subjects, we studied comparatively the pharmacokinetics and tolerance of three aminoglycoside antibiotics, gentamicin, sisomicin, and tobramycin. Serum concentrations were determined during 8 h and the urine recovery rate was determined within...

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Bibliographic Details
Main Authors: Lode, H., Kemmerich, B., Koeppe, P.
Format: Artigo
Language:Inglês
Published: 1975
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC429354/
https://ncbi.nlm.nih.gov/pubmed/1103722
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