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Recent advances in the development of farnesoid X receptor agonists

Farnesoid X receptors (FXRs) are nuclear hormone receptors expressed in high amounts in body tissues that participate in bilirubin metabolism including the liver, intestines, and kidneys. Bile acids (BAs) are the natural ligands of the FXRs. FXRs regulate the expression of the gene encoding for chol...

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Dades bibliogràfiques
Publicat a:Ann Transl Med
Autors principals: Ali, Ahmad H., Carey, Elizabeth J., Lindor, Keith D.
Format: Artigo
Idioma:Inglês
Publicat: AME Publishing Company 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293481/
https://ncbi.nlm.nih.gov/pubmed/25705637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2305-5839.2014.12.06
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