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Aberrant Histone Acetylation Promotes Mitochondrial Respiratory Suppression in the Brain of Alcoholic Rats

The acetylation of histone proteins in the core of DNA regulates gene expression, including those affecting mitochondria. Both histone acetylation and mitochondrial deficit have been implicated in neuronal damage associated with drinking problems. Many alcoholics will repeat unsuccessful attempts at...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Jung, Marianna E., Metzger, Daniel B.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293440/
https://ncbi.nlm.nih.gov/pubmed/25406171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.219311
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