Empirical Characteristics of Family-Based Linkage to a Complex Trait: the ADIPOQ Region and Adiponectin Levels

We previously identified a low frequency (1.1%) coding variant (G45R; rs200573126) in the adiponectin gene (ADIPOQ) which was the basis for a multipoint microsatellite linkage signal (LOD=8.2) for plasma adiponectin levels in Hispanic families. We have empirically evaluated the ability of data from...

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Publicado no:Hum Genet
Main Authors: Hellwege, Jacklyn N., Palmer, Nicholette D., Brown, W. Mark, Ziegler, Julie T., An, S. Sandy, Guo, Xiuqing, Chen, Y.-D. Ida, Taylor, Kent, Hawkins, Gregory A., Ng, Maggie C.Y., Speliotes, Elizabeth K., Lorenzo, Carlos, Norris, Jill M., Rotter, Jerome I., Wagenknecht, Lynne E., Langefeld, Carl D., Bowden, Donald W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293344/
https://ncbi.nlm.nih.gov/pubmed/25447270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-014-1511-8
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