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Transplanted Glial Restricted Precursor Cells Improve Neurobehavioral and Neuropathological Outcomes in a Mouse Model of Neonatal White Matter Injury Despite Limited Cell Survival

OBJECTIVE: Neonatal White Matter Injury (NWMI) is the leading cause of cerebral palsy and other neurocognitive deficits in prematurely-born children, and no restorative therapies exist. Our objective was to determine the fate and effect of glial restricted precursor cell (GRP) transplantation in an...

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Detalhes bibliográficos
Publicado no:Glia
Main Authors: Porambo, Michael, Phillips, Andre W., Marx, Joel, Ternes, Kylie, Arauz, Edwin, Pletnikov, Mikhail, Wilson, Mary Ann, Rothstein, Jeffery D., Johnston, Michael V., Fatemi, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293328/
https://ncbi.nlm.nih.gov/pubmed/25377280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22764
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