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TRKing down an old oncogene in a new era of targeted therapy

The employment of high-throughput next-generation sequencing techniques in multiple tumor types during the last few years has identified NTRK1, 2, and 3 gene rearrangements encoding novel oncogenic fusions in 19 different tumor types to date. These recent developments have led us to revisit an old o...

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Detalles Bibliográficos
Publicado en:Cancer Discov
Main Authors: Vaishnavi, Aria, Le, Anh, Doebele, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293234/
https://ncbi.nlm.nih.gov/pubmed/25527197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-14-0765
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